Autopneumonectomy with Compensatory Lung Growth
نویسندگان
چکیده
منابع مشابه
Compensatory Lung Growth After Pneumonectomy
Pneumonectomy, the surgical removal of a lung, elicits a number of anatomical changes within the thoracic cavity that augments the diffusion capacity of the remaining lung. Pneumonectomy directs the entire cardiac output into the remaining lung and creates an empty hemithorax that results in a shift of the mediastinum toward the vacated thoracic compartment. In a number of experimental animal m...
متن کاملSignals and mechanisms of compensatory lung growth.
Growth of the lung involves unique structure-function interactions not seen in solid organs. Mechanical feedback between the lung and thorax constitutes a major signal that sustains developmental as well as compensatory lung growth. After the loss of lung units as by pneumonectomy (PNX), increased mechanical stress and strain on the remaining units induce adaptive responses to augment oxygen tr...
متن کاملInvited Review HIGHLIGHTED TOPIC Lung Growth and Repair Signals and mechanisms of compensatory lung growth
Hsia, Connie C. W. Signals and mechanisms of compensatory lung growth. J Appl Physiol 97: 1992–1998, 2004; doi:10.1152/japplphysiol.00530.2004.— Growth of the lung involves unique structure-function interactions not seen in solid organs. Mechanical feedback between the lung and thorax constitutes a major signal that sustains developmental as well as compensatory lung growth. After the loss of l...
متن کاملNeoalveolarization contributes to compensatory lung growth following pneumonectomy in mice
Regeneration of gas exchange area by induction of neoalveolarization would greatly improve therapeutic options in destructive pulmonary diseases. Unilateral pneumonectomy is an established model to remove defined portions of gas exchange area and study mechanisms of compensatory lung growth. We addressed the question whether new alveoli are added to the residual lung after pneumonectomy in mice...
متن کاملNeoalveolarisation contributes to compensatory lung growth following pneumonectomy in mice.
Regeneration of the gas exchange area by induction of neoalveolarisation would greatly improve therapeutic options in destructive pulmonary diseases. Unilateral pneumonectomy is an established model to remove defined portions of gas exchange area and study mechanisms of compensatory lung growth. The question of whether new alveoli are added to the residual lung after pneumonectomy in mice was a...
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ژورنال
عنوان ژورنال: Canadian Respiratory Journal
سال: 2003
ISSN: 1198-2241
DOI: 10.1155/2003/853729